Rent one of Home In Italy’s high end traditional trullos or masserias transformed into large luxury villas available for weekly rentals in Salento area. These deluxe large family villas for rent are the perfect retreat for family gatherings or reunions with friends to enjoy an exclusive holiday in Salento, Puglia, one of the most beautiful and unspoilt regions of Italy. There’s a lot to explore in this part of Puglia. A visit to Otranto, a lovely seaside town with a charming historic center and a port, is not to be missed. During summer everyone goes to the beach clubs along the coast. Two more must-visit towns in the area are Monopoli and Polignano a Mare, both of which can be visited in a day. Then take a day during your vacation to visit Lecce, famous for its ornate Baroque architecture.